May 06, 2025
9 AM- 3:30 PM Eastern
New York Academy of Medicine 1216 5th Avenue New York, NY 10029
Conference
International studies led by the Director of the Seaver Autism Center for Research and Treatment, Joseph D. Buxbaum, PhD, MSc, and colleagues, have identified nearly 200 genes that, if changed, strongly contribute to autism. These discoveries also show that at least 25% of individuals with profound autism have genetic mutations.
Clinical researchers are now shifting their focus on treatments for autism. Rather than treating all autism as a single entity, we can now begin to look at genetically determined subtypes of autism and consider treatments that are tailored to the genetic subtype. This approach, called precision therapeutics, has revolutionized cancer treatment, and will revolutionize the treatment of profound autism.
Attend the conference to learn how researchers are identifying genetic mutations in autism, how the mutations lead to biologically-determined subtypes of autism, and how preclinical and clinical research are developing and testing new treatments for these subtypes. The interactions between academic scientists, families and advocacy groups, and industry partners will also be discussed, as precision therapeutics requires input from all these groups.
Program
Joseph D. Buxbaum, PhD, MSc - Developing Disease Modifying Therapeutics in Profound Autism
Director, Seaver Autism Center
Matthew Disney, PhD - Targeting RNA Structural Elements to enhance ASD Gene Expression
Institute Professor & Chair, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology
Fred Etoc, PhD - Drug Screening for Rare Neurodevelopmental Disorders Using Brain Micro-Tissues
Chief Scientific Officer, Rumi Scientific
Rachel Groth, PhD - Modulation of IGF-1 Signaling for the Treatment of Neurodevelopmental Synaptopathies
Vice President of Translational Science, Neuren Pharmaceuticals
Alex Kolevzon, MD - Developing Treatments in Phelan-McDermid Syndrome: Past, Present, and Future
Clinical Director, Seaver Autism Center
Professor, Psychiatry and Pediatrics; Director, Child and Adolescent Psychiatry
Mount Sinai Health System
Paige Siper, PhD - Measuring Outcomes in Profound Autism
Chief Psychologist, Seaver Autism Center, Associate Professor of Psychiatry
Pilar Trelles, MD - Maximizing Impact in Autism Research Through Inclusive Community Partnerships
Associate Chief Psychiatry, Outpatient Psychiatry Service, Boston Children's Hospital
Speaker Panel
Recordings of the presentations will be made available online following the conference.
While we will be able to provide verification of attendance, we will NOT be able to offer formal CME credit.
About the Advances in Autism Conference
The annual Conference is a one-day event hosted by the Seaver Autism Center for Research and Treatment at Mount Sinai. It includes a series of lectures given by accomplished professionals in the field of autism. The purpose of the conference is to discuss recent advances in autism - the causes, symptoms, and current and future treatments - with attendees. Conference attendees include practicing psychiatrists, neurologists, psychologists, geneticists, other health care professionals, neuroscientists, educators, family members and social workers.
Donation
If you are able, please consider donating to the Seaver Autism Center.
This gift will support the Seaver Center’s mission to provide affordable educational opportunities to the public to learn new and improved approaches to caring for people with autism.
If you would like to mail your donation, please mail a check to:Mount Sinai Health System, Attn: Patricia Carchi, One Gustave L. Levy Place, Box 1049, New York, NY 10029-6574
Icahn School of Medicine is a registered 501(c)3 nonprofit and contributions are tax-deductible the extent permitted by law. Tax-ID# 13-6171197 Please email [email protected] or contact Sarah Lynch at 212-241-0349 if you have any questions.