This is a medication study to evaluate whether a medication called propranolol can help reduce challenging behaviors in individuals with autism. Participation in this study may last up to 26 weeks (~6 months) and includes only 1-2 in-person visits to White Plains, NY or Staten Island, NY. In-person visits may be completed in the participant’s place of residence if needed. These visits will last 4-5 hours and can be split into multiple days. Study procedures will include medical and behavioral assessments including home blood pressure checks, EKGs and Holter monitor (a small wearable device that records heart activity). Ongoing weekly virtual visits with the study team may last up to 1 hour. Compensation will be provided for all study visits. Any travel, lodging, and meal expenses for the in-person site visits will be reimbursed.
We are looking for individuals aged 12–40 years with a diagnosis of autism who experience challenging behaviors, including aggression, self-injury or other disruptive behaviors that significantly impact their daily lives. All participants must be accompanied by a study partner who may be a parent, legal guardian, or other individual who spends at least 5 hours per week with the participant. Our team will complete a prescreening phone call to explain more about this study and answer any questions.
01/30/2026 - 12/31/2028
Northeast USA (ME, MA, NH, VT, RI, PA, MD, CT, NY, NJ )
Center for Autism and the Developing Brain and Institute for Basic Research; contact [email protected]
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